- 產品描述
落基山斑疹傷寒立克次體IgG免疫熒光玻片
Rickettsia rickettsii IgG IFA Kit
廣州健侖生物科技有限公司
主要用途:用于檢測人血清中的落基山斑疹傷寒立克次體IgG抗體
產品規格:12 孔/張,10 張/盒
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落基山斑疹傷寒立克次體IgG免疫熒光玻片
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【公司名稱】 廣州健侖生物科技有限公司
【】 楊永漢
【】
【騰訊 】 2042552662
【公司地址】 廣州清華科技園創新基地番禺石樓鎮創啟路63號二期2幢101-3室
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論文作者之一、加州索爾克生物研究所的胡安·卡洛斯·魯茲皮蘇阿-貝爾莫特說:“在老鼠身上進行的研究表明,這一過程迅速且安全,而且,這一方法繞過了在對人類細胞進行重組用于治療和再生目的方面長期存在的障礙。”
由誘導多能干細胞(iPS)產生的血細胞往往不能植入器官或骨髓中,而且也有可能引發腫瘤產生;而研究人員開發的這種名為“間接譜系轉化”的新技術耗時僅需兩周,也不會生成腫瘤,同時,以前的研究表明,這一新技術可被用來生成人類的血管細胞。
研究的主要作者、薩爾克研究所的研究員伊格納西奧·桑喬-馬丁內斯說:“我們并沒有讓皮膚細胞退回到干細胞狀態,而是利用新技術,讓皮膚細胞忘記了自己是什么,然后讓其轉化為我們所需要的細胞類型。在研究中,我們就讓其成功地轉化為了白血球。而且,誘導細胞失去記憶并引導其‘變身’為新細胞只需兩個生物分子。”
在研究中,科學家們借用新技術,將一個名為SOX2的分子變得具有可塑性,也就是讓其失去自己是某種特殊細胞類型的記憶,隨后,研究人員讓名為miRNA125b的遺傳因子,誘導細胞轉變成白血球。
目前,研究人員正在進行毒理學、細胞移植、預臨床研究和臨床研究之前的概念驗證等研究。他們表示,研究讓他們朝著利用干細胞移植治療人類疾病又邁近了一步。
Juan Carlos Luz Pissoua-Belmot, a co-author of the Salk Institute for Biology in California, said: "Studies conducted in mice have shown that this process is rapid and safe, and that this The approach bypasses the long-standing barrier in the reorganization of human cells for therapeutic and regenerative purposes. "
The blood cells produced by induced pluripotent stem cells (iPS) are often not implanted in organs or bone marrow, and may also cause tumorigenesis; while the newly developed new technique called "indirect lineage transformation" developed by researchers takes only two Weeks, will not generate tumors, the same time, previous studies have shown that this new technology can be used to generate human vascular cells.
The main author of the study, Ignacio Sancho Martínez, a researcher at the Salk Institute, said: "Instead of allowing skin cells to return to the stem cell state, we use new techniques that allow skin cells to forget that they are What and then let it be transformed into the type of cell we need. In the latest research, we successfully transformed it into white blood cells.Moreover, only two organisms are required to induce cells to lose their memory and lead them to 'transform themselves' into new cells molecular."
In the latest study, scientists borrowed new technology to make a molecule called SOX2 plastic, that is, letting it lose its memory as a particular type of cell. The researchers then led a genetic study called miRNA125b, Induce cells to turn into white blood cells.
Currently, researchers are conducting toxicology, cell transplantation, pre-clinical studies and proof-of-concept studies prior to clinical studies. They said the latest research has taken them one step closer to using stem cell transplantation to treat human disease.